2C-E is a 2C family psychedelic phenethylamine. Alexander Shulgin synthesized it first and documented it in his book PiHKAL. It produces sensory and cognitive effects in its physical reactions with living organisms, just like the other substances in its family.

2C-E was discovered in the 1970s by Alexander Shulgin, an American chemist, and has since gained some popularity for recreational use. However, in terms of abused substances, 2C-E is relatively uncommon. 2C-E, with reported street names such as Europa, Tootsie, and Aquarust, has previously been purchased online and shipped into the United States from countries such as China, according to ABC News. The drug’s hallucinogenic effects may be caused by its interaction with a specific type of serotonin receptor (5-HT2c) in the brain.

Designer drugs may be difficult to detect using conventional toxicology screening and laboratory testing. 1 Furthermore, because these drugs are illegal, it is difficult to know exactly what is in them, making them extremely dangerous and increasing the risk of an adverse reaction or fatal overdose.
Though most reports of 2C-E-related intoxication involve a younger demographic, another recently reported 2C-E-related mass poisoning involved 29 people ranging in age from 24-56.
Because it is relatively difficult to detect, the number of 2C-E related emergencies across the country may be underestimated.

The 2C class of drugs is classified as psychedelics (hallucinogens), but they can also have stimulant effects. They can cause hallucinations (seeing and hearing things that aren’t there) as hallucinogens because they distort reality.
They can make you feel awake, alert, and affectionate towards those around you as stimulants.
The 2C drugs can make you: energized and alert; hypersensitive to colors, sounds, and smells; and sexually aroused.

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